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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd5eda327a098fd55b383eed347d33fb5c3b980ba34c5907c6fcace008ac81ecc' 
  AND token = 'QhpSfmEwm/WBeP61eeQtdljJGMDisQ8QLy+swa7ZjMQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}