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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c485583f4ffc4f7325597ab0c609a52aa5e5b2548393ae4a763a925d3dc38822' 
  AND token = 'l/Gnac3uQATgcc3LbXDdeyLgw/R7pdCvQk1DHUnlidQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}