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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '396a059ecf90b3a02c170b9bc42b4e7bda0d64e1149ae34c9172e72e3e96d1b0' 
  AND token = 'YV5yuvmfNxwltHlYfXVvgLP8MsyAIQuo+N9BlVIY/o4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}