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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ecbe10f188cb647c26a7717a576b3ee0dc7f555260ac706a0e5042aead49848' 
  AND token = 't4w8rLZZI83Yia52O6bjBjyOnjjQ4dDTMOPRe6gVGKs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}