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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd1b347a5d53528dd5cbc350eb9cfb9924c56ddcc796f77f3fc607364dfc4d493' 
  AND token = 'tDbFiAHcWZXke+EUcOXVvUdNNPq+jQaRwJnLXtwBFDE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}