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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '282ed2ab88cbdc97473f89fe633a8f300e98e4283113b8e76f26753e49702676' 
  AND token = 'ceUH9xtG2xv2XZH9Fz4vt5TPAMYE9S27qnG5aCL/oSE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}