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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b51bc87c2cb29762d3e29dffc6ea3eea419bb8fbf79799838dd03cdcc7cc2fd7' 
  AND token = 'wmlvjBr1+i9oGj7vem2TvZSkwFpBBB6/3L6M+pdc1vA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}