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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b18a41ecd68d53eac9d51399e3c60a68168a1f4a5d12421b37a17405ea667aa0' 
  AND token = 'TF60Uhdz60HfLsoFnZk/ol9ML0sF0f6zNYnCbIgptAY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}