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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d37e8a009ae971f695ef6a1c9a61b4b540960412c0aa20a43c584112702f916' 
  AND token = 'StDXt86BRIzfFvyhg2b8V/qTyWUaD0gTRgtbFu3JtEo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}