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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8df189b3f88300a3064beff21c051dc64ef4974138f3abbd862b9889a9c1c884' 
  AND token = '8gdXLqCw5NQ8WBDCeC1jTPiGLOLFq7NHXlBEPv54afI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}