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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b1784e8fe11e4926448406b1aeb1da3d2c14efe7c19ecfed8196ee8266fb17d8' 
  AND token = 'VmPrEisttRzZ2X2LO9jH+UwLHBdgbqlk61paf7W0IgU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}