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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ca8b4e79c5915b813d2b348802ec89b8983535790456271e966e097b7054af3c' 
  AND token = '52NxUekgS5vomnQjaiQacrHlg8/ujcCz3ftDrudLIOo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}