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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f9ed4ac1c1fc665e080d2d6a7dc2ea234229e0060d8b024b8f1d11682c0516ef' 
  AND token = '0yAxsbLHNYDdiWfAqfpXfUdNF9M7PKyOmudJxNY2yi8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}