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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8893c5d239fbc7b3d0e96da3fac54c3a2eed145ed433082f563eed7857e9b281' 
  AND token = 'rnA1ydc/w1zcS9btkrSxNhK/qmXmlw+XWRqP9EHpB+8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}