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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e278bf213dadb2ce5b0123368039da3112997a4467a1d1025df96c845ea386b1' 
  AND token = 'HRFOy01MyB/qkkcl1XOpmBOQ4/HzQdImyR1guyzH+1I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}