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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f5fa671310c87b34a56e1dfd6d125b680a62ad7d03c997a693558515dc71c71' 
  AND token = 'r2pm8U4UvY/wGn8nSTqUwu2vXBAy3cHP8R9XlkN1FOE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}