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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '259ad8c28bb2f94b46bd05cd6768125c37ebcc372a3497689998f231b451b0a4' 
  AND token = 'YLTo3r5hI1F+/2qutqGaH17/gKrECN0fLntxTFPdC2A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}