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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72bcb799caaa4b188b8b466c2a3ee2018307c679a9604efb199ed477fdedd71c' 
  AND token = 'GbOP5WOiXNAN6mFxj/iVKnNCxtz3uCGyXTDjTlSFDLA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}