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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f8d1182be252cd5e3883041237e40dd45224d97fff25bc2c9e9cf5157701b169' 
  AND token = 'Q5c8BpFICYo7w8x8eDhH4JMufw+B/ZxJ6KLwx0RLL/w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}