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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c1c791d4cf4b2ecf0554fcb6be22527ed73ecdc5a09b571b72ba8949383d9aa9' 
  AND token = 'U+uxMJTJXMxakYFEcmCL3C+gxTG12fk+y+0JR1MfW8A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}