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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9f9a926ce4399350785ce59d360dd31ee46ca6978256a3ce9cf26cbd438d4a91' 
  AND token = 'A87TRrxQLaRd54m+5uKTwyz1q23ZSTbLfyjUPm34dFQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}