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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '268a5b5c21a7b8e63d17be84d37df1bbc39702c2bf5637161a1c9dc1234e06b4' 
  AND token = 'YOqbPAX2JJsB/2FxNC1NS9tve9enhyRZgjecD+zq1aM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}