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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0b46ee3c616eb1638fec1e4bb56e3bf256a3e7cc5d93261739da4c9ff0768d91' 
  AND token = 'spBENbUiTxLjHMxEEvk2egyzqkU/Jfc8JtXWIV3WotU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}