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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c6729ae0367faef8e1a20a472c12cda55ed723dd1f3f4b9b0c36f9ffeeb0a454' 
  AND token = 'IYULUjCJLyGBGco9UlzcWcJNPPDk8aoSQERwX7gV4D0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}