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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3b8d0657067425fa8e7b4525cede5ddfd15a27023fc8a6d24b9862606f271816' 
  AND token = 'C0G6BgCOaQJfFv3CRyrFtSBWq9QXw2QO79nDcaYAR7s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}