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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7c778ec3090e80e67c24043b006e734228aee4d1d3faa4c66c0e872e617446af' 
  AND token = 'fwWCELnqp4oNXKnSe6D+Ar6jiV/XfH34lb4Rp6YT6no=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}