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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b5775fb58de5bd78ced6154eec4196ec882c5e2102c7b1e9648a66f91f0aba1e' 
  AND token = 'UzInqHEVwPYO88i074qpqTZpAhcbk5jcG2RFO1zc1AU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}