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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c547ac543a0c91ace1acd26979a4002135a1ee48e20a00eea24de90bdaec96a5' 
  AND token = 'os6p5in3rgnIm9QQ0bpgJja0kTxcKQ/cQu5e/S9NJC0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}