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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '62cfdea47b8a5b495c585e8874e921885d7b52e39be28993aae1fce2bad9607a' 
  AND token = 'ljsP6WrkGYSZPUvsF3WrxtLDbi8JQ6WEV24XE0RvwUU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}