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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0897ffe13bbc9e1133176c101c946fd3113f8890d6cf8c1d1e1875165c8c7490' 
  AND token = 'nyslBv9cm6fJx+LXhPKG2RRUyFpAx51JHJalz3A5KwA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}