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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4bfc78d93dd34c5ca3542d10aad0403a57c8ee32b5a53d735a436e12e72d97e4' 
  AND token = 'JCQD6de3WeVI0NLh7D7llxP+26gkTxanG66dPCp4bp4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}