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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ab2ddc6972be21f150af4d4da26a7ec5c61b25dd1bc2f0b8250785f92d1be254' 
  AND token = 'DxTCcr668q+dn0ceb4W1Jr2+Ir/AxwHYYx2EaKmfg00=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}