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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de6acf40cddd0ecbaad0cb20422b9b45012cc977619007390e1b9f2a53014061' 
  AND token = 'FK3n3P9tWo8dTy6DThspmbIDAI0437HSrbQyu7O1Sd8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}