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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a243162767118d047ae0fd5e281d82e2e0ae8b75576c171611191c109304ac37' 
  AND token = 'QMVP+n0TeZznCOOTxRgsBm9sDc2HdXpD3EEqUsyZ/Gw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}