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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e8c81f099f147639b2ce05b401927479adc490626a9a72a2e95a3ead4dbe29cd' 
  AND token = '/GJUj526G3dVdsPhDGEEhtLVPEQ/fwls1QPa2UWUtRc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}