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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c8882746d050aea9809f7a51bd700a45819dd93ae6744af2be8a60e0fb0d0f72' 
  AND token = 'yE9S8IDe0qXVX85aTQ7b/L/+4kZ3IUYw2tk+hLricmM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}