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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '129a3ee7b4a04014f87e4e558eaf52cc3cf6914731dc8000e1164ae0efa3d581' 
  AND token = 'AVD/Pf2trMxJxFpBSqRsoMaaext/gJ/9m0vg17dIkm0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}