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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e6e25805ccff5da8115cfa895584b4eaf44c34c5cf70f1f4e5cb268810e8a7ec' 
  AND token = 't0+E9Ua/d4v7LCGIW8Eu96Shcx94RTHM0ILJt/7Ybw8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}