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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9580b998154b8800996e929a77e77c712d9c908bf57636c8155bb14a868b8a6b' 
  AND token = 'P0H1reYY5IUDqd+JWvYPtVqxhw8KOaq4xoHlTbCzkpk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}