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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '86a1e7814a5174164f05d3cfb6846fbec1ee58a076c164cbb5e1e9b213b4437f' 
  AND token = 'iH3+VrHA59lYywWCwvrkB+nn5Vw8jB+rxs7eeXOlK+g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}