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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6607fa12ea7d58ff30d11b151d0129da78aea1d90d928bbaf6a3b3dd98ee0f90' 
  AND token = 'WpBwlSo4LBCPNnla2j0DfJMsvgEblYCWVcoErfYFiSc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}