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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e0bd2a74a10e4978d401a60da19bdc34741c412d1c6b375c8306fac745c9feca' 
  AND token = 'HCBRU9nXatFKhe0vigVmxlKfREu5/DCOTtaiRC+T34I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}