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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '447ab8fc198312d44d247300a8d108b81849323dee36579f29a70e7047a92b98' 
  AND token = 'Erea2X95oFwB7ku2HgV6TJgBBBHUPP3WfQV2DNtI8xE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}