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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '808e22fed8ef9c9b29d470d3f67b6e71a9ba14354d3ca30122afdeaf46641f02' 
  AND token = 'Tf4wBDVPErXH6rM6M1oCprDxUSF28s8+Adb7HsaxCBY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}