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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f1cd68d8446c6b956b383fe04ffa8095a2b5ae441b525693553cbae232aee525' 
  AND token = 'jvyLn4N5Uv6E1LmQ7SL9imxDTR8se1XN/JQUQtAFtqk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}