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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f068fc8df50b4d5a71193e613c99d94003a86681143d84418a68d1022132d5b' 
  AND token = 'PjxXDQiqVUuV+215Hhf2Ez0LbvK3ie1T2JyV74r4PYc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}