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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '516fe1dbb1c8e12723aa958b5a2add08d94164584a9262d003dfbf962c51c91e' 
  AND token = 'wUXoSTsr7ET8NhxEOEBCGtlrz2awocg3feuhKwD2MmA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}