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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ce8a8816c48d6960192ed3f60018c57d69540f6f40fe6ff06b09a55deec2c77a' 
  AND token = 'n4dGLr+jnj+FO20oITdVE+8a/M1RBttuVzUieRz0JbI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}