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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd59b8f470d4f7a75692205e5e2c0bc15fdd0a16bdcfb4d0bc8571d849e70ae45' 
  AND token = 'cTDgkJWjtEqMmd1SEeKe7iAi42KhaLbj7ijvzcBLerA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}