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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2f0d3ad0870a6bc27cd226331b6286e6861c3fb85e297b90c834cd576e92bcd5' 
  AND token = 'Rcm42vWZqLJeSu0K4KT3WVkb95/ahN2G+MxkuTgFTdc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}